Narcotic Opiods Addiction
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Narcotic addiction is life a threatening condition that can lead to physiologic and psychological dependence.  Narcotics,  class of drugs that includes opiods,,  utilized to treat pain.  Cocaine is also considered a narcotic. Often, through continued usage, narcotics lead to tolerance that can then lead to addiction.  

Opiods act by binding to the opioid-U receptors or the "reward pathway."  With regular and continued use the brain stops producing natural pain killing neuro-chemicals, and relies on outside supplementation. As the user develops more tolerance they then develop dependence.  Failure to provide the drug to the brain, the patient undergoes withdrawal. 

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Buprenorphine for the management of opioid withdrawal.
Cochrane Database Syst Rev. 2004 Oct 18;(4):CD002025.
PMID: 15495026